Sntn Protein (AA 1-147) (His tag)
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- Antigène Voir toutes Sntn Protéines
- Sntn (Sentan, Cilia Apical Structure Protein (Sntn))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-147
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Sntn protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- SNTN, 1-147aa, Human, His tag, E.coli
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product Sntn Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol, 0.15M NaCl, 1mM DTT
- Stock
- 4 °C
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- Antigène
- Sntn (Sentan, Cilia Apical Structure Protein (Sntn))
- Autre désignation
- SNTN (Sntn Produits)
- Synonymes
- S100A1L Protein, S100AL Protein, sentan Protein, A430083B19Rik Protein, sentan, cilia apical structure protein Protein, SNTN Protein, Sntn Protein
- Sujet
- SNTN, also known as sentan, belongs to the S-100 family. SNTN is shown to localize exclusively to the bridging structure between the cell membrane and peripheral singlet microtubules, which specifically exists in the narrowed distal portion of cilia. Exogenously expressed sentan showed affinity for the membrane protrusions, and a protein-lipid binding assay revealed that sentan bound to phosphatidylserine. These findings suggest that sentan is the first molecular component of the ciliary tip to bridge the cell membrane and peripheral singlet microtubules, making the distal portion of the cilia narrow and stiff to allow for better airway clearance or ovum transport. Recombinant human SNTN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Sentan, S100A1L, S100AL. NCBI no.: NP_001074006
- Poids moléculaire
- 18.6 kDa (167aa), confirmed by MALDI-TOF
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