CHMP3 Protein (AA 1-222) (His tag)

N° du produit ABIN667482

Détail du produit

Antigène: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-222

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CHMP3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: VPS24, 1-222aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT

Stock: 4 °C

Détail du antigène

Antigène: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Autre désignation: VPS24 (CHMP3 Produits)

Synonymes: CG9779 Protein, Dmel\\CG9779 Protein, Vps24 Protein, dvps24 Protein, vps24 Protein, VPS24 Protein, CHMP3 Protein, GB15107 Protein, wu:fb47g01 Protein, zgc:76972 Protein, NEDF Protein, 25.1 Protein, 4921505F14Rik Protein, 9130011K15Rik Protein, CGI-49 Protein, D6Ertd286e Protein, Vacuolar protein sorting 24 Protein, charged multivesicular body protein 3 Protein, SNF7 family protein Protein, hypothetical protein Protein, neuroendocrine differentiation factor, putative Protein, charged multivesicular body protein 3 S homeolog Protein, Vps24 Protein, chmp3 Protein, VPS24.2 Protein, CpipJ_CPIJ004098 Protein, PGTG_02107 Protein, LOC5569267 Protein, Smp_032150 Protein, CHMP3 Protein, LOC410607 Protein, Chmp3 Protein, chmp3.S Protein

Sujet: VPS24, also known as Charged multivesicular body protein 3(CHMP3), belongs to the vacuolar sorting protein family and function as chromatin modifying proteins. It associates directly with CHMP2 and CHMP4 for the disassembly of ESCRT-III complex in an ATP-dependent manner. During HIV-1 infection, the virus uses the ESCRT-III complex to mediate budding and exocytosis of viral proteins. Overexpression of VPS24 strongly inhibits HIV-1 release. Recombinant human VPS24 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Charged multivesicular body protein 3, CGI-149, CHMP3, FLJ38114, NEDF. NCBI no.: NP_057163

Poids moléculaire: 27.2 kDa (242aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)