DCUN1D2 Protein (AA 1-259) (His tag)

N° du produit ABIN667515

Détail du produit

Antigène: DCUN1D2 (DCN1, Defective in Cullin Neddylation 1, Domain Containing 2 (DCUN1D2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-259

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette DCUN1D2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: DCUN1D2, 1-259aa, Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl

Stock: 4 °C

Détail du antigène

Antigène: DCUN1D2 (DCN1, Defective in Cullin Neddylation 1, Domain Containing 2 (DCUN1D2))

Autre désignation: DCUN1D2 (DCUN1D2 Produits)

Synonymes: C13orf17 Protein, RGD1311743 Protein, AW495713 Protein, mFLJ10704 Protein, defective in cullin neddylation 1 domain containing 2 Protein, DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae) Protein, DCUN1D2 Protein, Dcun1d2 Protein

Sujet: DCN1-like protein 2, also known as DCUN1D2, which contains one DCUN1 domain and 1 UBA-like domain, may play a role in the neddylation of cullins that regulate SCF-type ubiquitin ligase complexes. The gene encoding Dcun1D2 exists on human chromosome 13. Chromosome 13 houses key tumor suppressor genes, including BRCA2 and RB1, which are associated with breast cancer susceptibility and retinoblastoma, respectively. Recombinant human DCUN1D2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: defective in cullin neddylation protein 1(DCN1)-like protein 2, DCUN1L2. NCBI no.: NP_001014305

Poids moléculaire: 32.3kDa (279aa), confirmed by MALDI-TOF