FKBP1B Protein (AA 1-108) (His tag)

N° du produit ABIN667593

Détail du produit

Antigène: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Type de proteíne: Recombinant

Attributs du protein: AA 1-108

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette FKBP1B protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: FKBP1B, 1-108aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT

Stock: 4 °C

Détail du antigène

Antigène: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Autre désignation: FKBP1B (FKBP1B Produits)

Synonymes: FKBP12.6 Protein, MGC68829 Protein, FKBP1B Protein, DKFZp459K1429 Protein, 12.6kDa Protein, AW494148 Protein, calstabin2 Protein, FKBP1L Protein, OTK4 Protein, PKBP1L Protein, PPIase Protein, FK506 binding protein 1B Protein, FK506 binding protein 1B L homeolog Protein, FK506 binding protein 1b Protein, FKBP1B Protein, fkbp1b.L Protein, fkbp1b Protein, Fkbp1b Protein

Sujet: FKBP1B, also known as peptidyl-prolyl cis-trans isomerase FKBP1B, is a member of the immunophilin protein family which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus). It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. Recombinant human FKBP1B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Peptidyl-prolyl cis-trans isomerase FKBP1B, FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase. NCBI no.: NP_004107

Poids moléculaire: 14.2 kDa (130aa), confirmed by MALDI-TOF

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity