GMDS Protein (AA 1-372) (His tag)

N° du produit ABIN667602

Détail du produit

Antigène: GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))

Type de proteíne: Recombinant

Attributs du protein: AA 1-372

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GMDS protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: GMDS, 1-372aa, Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.1M NaCl,1mM DTT, 0.1mM PMSF

Stock: 4 °C

Détail du antigène

Antigène: GMDS (GDP-Mannose 4,6-Dehydratase (GMDS))

Autre désignation: GMDS (GMDS Produits)

Synonymes: BC031788 Protein, C87208 Protein, GMD Protein, SDR3E1 Protein, GDP-mannose 4, 6-dehydratase Protein, GDP-mannose 4,6-dehydratase Protein, Gmds Protein, GMDS Protein

Sujet: GMDS, also known as SDR3E1, belongs to the GDP-mannose 4,6-dehydratase family. This protein utilizes NADP as a cofactor to catalyze the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose. Mutations in the gene encoding GMDS are involved in resistance to TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)-induced apoptosis. Recombinant human GMDS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: GDP-mannose 4,6 dehydratase, GMD, SDR3E1. NCBI no.: NP_001491

Poids moléculaire: 44.1 kDa (392aa), confirmed by MALDI-TOF