NFKBIB Protein (AA 1-356) (His tag)

N° du produit ABIN667688

Détail du produit

Antigène: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Type de proteíne: Recombinant

Attributs du protein: AA 1-356

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NFKBIB protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: NFKBIB, 1-356aa , Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT

Stock: 4 °C

Détail du antigène

Antigène: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Autre désignation: NFKBIB (NFKBIB Produits)

Synonymes: NFKBIB Protein, IKB-beta Protein, IKappaBbeta Protein, IkB Protein, IkBb Protein, IKBB Protein, TRIP9 Protein, NFKB inhibitor beta Protein, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta Protein, NFKBIB Protein, Nfkbib Protein

Sujet: NFKBIB, also known as NF-kappa-B inhibitor beta, belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Recombinant human NFKBIB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: IKBB, TRIP9. NCBI no.: NP_002494

Poids moléculaire: 40.3 kDa (380aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades