Frataxin Protein (FXN) (AA 42-210) (His tag)

N° du produit ABIN667758

Détail du produit

Antigène: Frataxin (FXN)

Type de proteíne: Recombinant

Attributs du protein: AA 42-210

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Frataxin protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: Frataxin, 42-210aa, Human, His tag, E.coli

Pureté: > 95 % by SDS-PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.

Stock: 4 °C

Détail du antigène

Antigène: Frataxin (FXN)

Autre désignation: Frataxin (FXN Produits)

Synonymes: zgc:158218 Protein, LOC100284365 Protein, BcDNA:AT09528 Protein, CG8971 Protein, DFH Protein, Dfh Protein, Dmel\\CG8971 Protein, X25 Protein, dfh Protein, CyaY Protein, FA Protein, FARR Protein, FRDA Protein, RGD1565754 Protein, Frda Protein, frataxin Protein, fxn Protein, LOC100284365 Protein, TVAG_182150 Protein, fh Protein, FTX1 Protein, FXN Protein, Fxn Protein

Sujet: Frataxin, also known as FXN, is an iron binding protein which belongs to FRATAXIN family. It is an anti-apoptotic protein which prevents mitochondrial damage, reactive oxygen species production and act as either an iron chaperone or an iron storage protein. Frataxin is localized to the mitochondrion and regulating mitochondrial iron transport and respiration. Defects in this protein cause Friedreich ataxia. Recombinant Frataxin protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CyaY, FA, FARR, FRDA, X25, FXN, Friedreich ataxia protein. NCBI no.: NP_000135

Poids moléculaire: 21.1 kDa (190aa), confirmed by MALDI-TOF.

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size