AKR7A2 Protein (AA 1-359) (His tag)

N° du produit ABIN667763

Détail du produit

Antigène: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-359

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette AKR7A2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: AKR7A2, 1-359aa, Human, His tag, E. coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 20% glycerol

Stock: 4 °C

Détail du antigène

Antigène: AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Autre désignation: AKR7A2 (AKR7A2 Produits)

Synonymes: AFAR Protein, AFAR1 Protein, AFB1-AR1 Protein, AKR7 Protein, Aiar Protein, akr7a2 Protein, aldo-keto reductase family 7 member A2 Protein, aldo-keto reductase family 7, member A2 Protein, aldo-keto reductase family 7, member A2 L homeolog Protein, AKR7A2 Protein, Akr7a2 Protein, akr7a2.L Protein

Sujet: Aldo-keto reductases, such as AKR7A2, are involved in the detoxification of aldehydes and ketones. This protein can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the nonbinding AFB1 dialcohol. It may be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Also, it has been proposed previously to catalyze the NADPH-dependent reduction of succinic semialdehyde (SSA) to gamma-Hydroxybutyrate in human brain. Recombinant AKR7A2 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Aflatoxin B1 aldehyde reductase member 2, AFAR, AFAR1, AFB1-AR1, AKR7, aldo-keto reductase family 7, member A2 AFB1 AR1, AFB1AR1, aflatoxin aldehyde reductase, aflatoxin beta1 aldehyde reductase, Aiar, aldo keto reductase family 7, aldo keto reductase family 7, member A2, aldoketoreductase 7. NCBI no.: NP_003680

Poids moléculaire: 44.0kDa (398aa), confirmed by MALDI-TOF.