Aspartate beta Hydroxylase Protein (AA 75-270) (His tag)

N° du produit ABIN667766

Détail du produit

Antigène: Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Type de proteíne: Recombinant

Attributs du protein: AA 75-270

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Aspartate beta Hydroxylase protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: ASPH, 75-270aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Autre désignation: ASPH (ASPH Produits)

Synonymes: AAH Protein, BAH Protein, CASQ2BP1 Protein, HAAH Protein, JCTN Protein, junctin Protein, 2310005F16Rik Protein, 3110001L23Rik Protein, AI848629 Protein, AW261690 Protein, AW561901 Protein, C79816 Protein, cI-37 Protein, aah Protein, bah Protein, jctn Protein, MGC107896 Protein, cb971 Protein, fb69e10 Protein, fc06d04 Protein, fc95a08 Protein, wu:fb69e10 Protein, wu:fc06d04 Protein, wu:fc95a08 Protein, aspartate beta-hydroxylase Protein, aspartate-beta-hydroxylase Protein, aspartate beta-hydroxylase L homeolog Protein, ASPH Protein, Asph Protein, asph Protein, asph.L Protein

Sujet: ASPH (Aspartate beta-hydroxylase) is a widely-expressed type II membrane protein involved in calcium homeostasis. Located in the endoplasmic reticulum, ASPH specifically hydroxylates an Asp or Asn residue in the epidermal growth factor-like (EGF) domains of several proteins, using iron as a cofactor. While all ASPH variants are expressed in skeletal muscle, only some are detected in heart, brain, pancreas, placenta, lung, liver, and kidney tissues. Recombinant human ASPH protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: AAH, BAH, CASQ2BP1, HAAH, JCTN, junctin, Aspartyl/asparaginyl beta-hydroxylase ASP beta hydroxylase, Aspartyl/asparaginyl beta hydroxylase, Peptide aspartate beta dioxygenase,. NCBI no.: NP_001158227

Poids moléculaire: 24.5 kDa (217aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)

Pathways: Positive Regulation of Endopeptidase Activity