Aspartate beta Hydroxylase Protein (AA 341-758) (His tag)

N° du produit ABIN7273878

Détail du produit

Antigène: Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Type de proteíne: Recombinant

Attributs du protein: AA 341-758

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Aspartate beta Hydroxylase protéine est marqué à la His tag.

Fonction: Human ASPH Protein

Séquence: Ile341-Ile758

Attributs du produit: Recombinant Human ASPH Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ile341-Ile758.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl ( pH 7.4).

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Autre désignation: ASPH (ASPH Produits)

Synonymes: AAH Protein, BAH Protein, CASQ2BP1 Protein, HAAH Protein, JCTN Protein, junctin Protein, 2310005F16Rik Protein, 3110001L23Rik Protein, AI848629 Protein, AW261690 Protein, AW561901 Protein, C79816 Protein, cI-37 Protein, aah Protein, bah Protein, jctn Protein, MGC107896 Protein, cb971 Protein, fb69e10 Protein, fc06d04 Protein, fc95a08 Protein, wu:fb69e10 Protein, wu:fc06d04 Protein, wu:fc95a08 Protein, aspartate beta-hydroxylase Protein, aspartate-beta-hydroxylase Protein, aspartate beta-hydroxylase L homeolog Protein, ASPH Protein, Asph Protein, asph Protein, asph.L Protein

Sujet: Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis.

Poids moléculaire: 49.2 kDa same as Tris-Bis PAGE result.

Pathways: Positive Regulation of Endopeptidase Activity