PKLR Protein (AA 47-574) (His tag)

N° du produit ABIN667822

Détail du produit

Antigène: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Type de proteíne: Recombinant

Attributs du protein: AA 47-574

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PKLR protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PKLR, 47-574aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 1mM DTT, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Autre désignation: PKLR (PKLR Produits)

Synonymes: PK1 Protein, PKL Protein, PKR Protein, PKRL Protein, RPK Protein, Pklg Protein, wu:fd15e01 Protein, wu:fi37e08 Protein, pk1 Protein, PKLR Protein, Pk-1 Protein, Pk1 Protein, R-PK Protein, pklr Protein, pyruvate kinase L/R Protein, pyruvate kinase, liver and RBC Protein, pyruvate kinase, liver and RBC L homeolog Protein, pyruvate kinase liver and red blood cell Protein, pyruvate kinase PKLR-like Protein, PKLR Protein, Pklr Protein, pklr Protein, pklr.L Protein, LOC100621940 Protein

Sujet: PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. The PKLR gene encodes the L- and R-type isoenzymes through alternative splicing events under the control of different promoters. The L-type isoform also exists as a tetramer and is upregulated by glucose with implications in maturity-onset diabetes of the young. Recombinant human PKLR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Pyruvate kinase isozymes R/L, PK1, PKL, PKR, PKRL, RPK. NCBI no.: NP_000289

Poids moléculaire: 59.2 kDa (549aa), confirmed by MALDI-TOF

Pathways: Ribonucleoside Biosynthetic Process