Thymidine Phosphorylase Protein (TYMP) (AA 11-482) (His tag)

N° du produit ABIN667826

Détail du produit

Antigène: Thymidine Phosphorylase (TYMP)

Type de proteíne: Recombinant

Attributs du protein: AA 11-482

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Thymidine Phosphorylase protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: TYMP, 11-482aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: Thymidine Phosphorylase (TYMP)

Autre désignation: TYMP (TYMP Produits)

Synonymes: ECGF Protein, ECGF1 Protein, MEDPS1 Protein, MNGIE Protein, MTDPS1 Protein, PDECGF Protein, TP Protein, hPD-ECGF Protein, 2900072D10Rik Protein, Ecgf1 Protein, PD-ECGF Protein, Pdgfec Protein, typh Protein, thymidine phosphorylase Protein, thymidine phosphorylase DeoA Protein, AMP phosphorylase Protein, Thymidine phosphorylase Protein, TYMP Protein, Tymp Protein, deoA Protein, Dd586_0614 Protein, Kvar_4413 Protein, NMAG_RS19330 Protein, Snov_1187 Protein, Fbal_2856 Protein, Ftrac_2071 Protein, Intca_1216 Protein, ARCVE_RS10415 Protein, Sphch_4174 Protein, Sinme_3461 Protein, METOK_RS06355 Protein, Mesop_1831 Protein, typh Protein

Sujet: Thymidine phosphorylase precursor, also known TYMP, is a platelet-derived endothelial cell growth factor that catalyzes the formation of thymine and 2-deoxy-D-ribose-1-phosphate from thymidine and orthophosphate. It is an angiogenic inducer that potently stimulates the growth of endothelial cells and induces chemotaxis. Increased expression of TYMP is seen in a wide variety of different solid tumors and inflammatory diseases and is often associated with poor prognosis. Recombinant human TYMP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ECGF1, hPD-ECGF, MNGIE, PDECGF, TP, Gliostatin, Thymidine phosphorylase. NCBI no.: NP_001107228

Poids moléculaire: 51.3 kDa (493aa), confirmed by MALDI-TOF

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2