HPD Protein (AA 1-393) (His tag)
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- Antigène Voir toutes HPD Protéines
- HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-393
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette HPD protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- HPD, 1-393aa, Human, His tag, E.coli
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product HPD Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 50mM NaCl
- Stock
- 4 °C
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- Antigène
- HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))
- Autre désignation
- HPD (HPD Produits)
- Synonymes
- fb58f02 Protein, hpd Protein, wu:fb58f02 Protein, zgc:56326 Protein, zgc:92456 Protein, MGC146689 Protein, BA0240 Protein, PSPTO3553 Protein, DDBDRAFT_0203373 Protein, DDBDRAFT_0231603 Protein, DDBDRAFT_0231604 Protein, DDB_0203373 Protein, DDB_0231603 Protein, DDB_0231604 Protein, hppd Protein, 4-HPPD Protein, 4HPPD Protein, GLOD3 Protein, HPPDASE Protein, PPD Protein, 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE Protein, F12K11.9 Protein, F12K11_9 Protein, HPD Protein, P-HYDROXYPHENYLPYRUVATE DIOXYGENASE Protein, phytoene desaturation 1 Protein, Fla Protein, Flp Protein, Hppd Protein, Laf Protein, 4-hydroxyphenylpyruvate dioxygenase a Protein, 4-hydroxyphenylpyruvate dioxygenase Protein, 4-hydroxyphenylpyruvate dioxygenase b Protein, 4-hydroxyphenylpyruvate dioxygenase L homeolog Protein, 4-hydroxyphenylpyruvic acid dioxygenase Protein, hpda Protein, HPD Protein, hpdb Protein, hpd.L Protein, hpd Protein, BA_0240 Protein, hppD Protein, Hpd Protein, PDS1 Protein
- Sujet
- 4-hydroxyphenylpyruvate dioxygenase isoform 1, also known as HPD, is an Fe-containing enzyme, that catalyzes the second reaction in the catabolism of tyrosine the conversion of 4-hydroxyphenylpyruvate to homogentisate. Existing as a homodimer, HPD uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. Defects in the gene encoding HPD are the cause of tyrosinemia type 3 and hawkinsinuria, both of which are inborn errors of metabolism that are associated with a variety of symptoms, including mental retardation and seizures and hair and urine abnormalities. Recombinant human HPD protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: 4-hydroxyphenylpyruvate dioxygenase isoform 1, 4-HPPD, 4HPPD, GLOD3, HPPDASE, PPD. NCBI no.: NP_002141
- Poids moléculaire
- 47 kDa (413aa) confirmed by MALDI-TOF
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