HAGH Protein (AA 1-260) (His tag)

N° du produit ABIN667841

Détail du produit

Antigène: HAGH (Hydroxyacylglutathione Hydrolase (HAGH))

Type de proteíne: Recombinant

Attributs du protein: AA 1-260

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HAGH protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: HAGH, 1-260aa, Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl Buffer (pH 8.5) containing 10% Glycerol

Stock: 4 °C

Détail du antigène

Antigène: HAGH (Hydroxyacylglutathione Hydrolase (HAGH))

Autre désignation: HAGH (HAGH Produits)

Synonymes: glo-2 Protein, glo2 Protein, glx2 Protein, glxii Protein, hagh1 Protein, DDBDRAFT_0186675 Protein, DDBDRAFT_0230988 Protein, DDB_0186675 Protein, DDB_0230988 Protein, DDBDRAFT_0183924 Protein, DDBDRAFT_0230991 Protein, DDB_0183924 Protein, DDB_0230991 Protein, BC019817 Protein, Glo-2 Protein, Glo2 Protein, Rsp29 Protein, RSP29 Protein, fa66a03 Protein, wu:fa66a03 Protein, zgc:73161 Protein, GLO2 Protein, GLX2 Protein, GLXII Protein, HAGH1 Protein, hydroxyacylglutathione hydrolase L homeolog Protein, hydroxyacylglutathione hydrolase Protein, beta-lactamase domain-containing protein Protein, hydroxyacyl glutathione hydrolase Protein, hagh.L Protein, CND02510 Protein, gloB1 Protein, gloB2 Protein, Fbal_1466 Protein, Hagh Protein, hagh Protein, HAGH Protein

Sujet: HAGH is a member of the glyoxalase family and a thiolesterase which hydrolyses S-lactoyl-glutathione to reduced glutathione and D-lactate. This protein is a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73 and serves as a pro-survival factor of the p53 family. It exists only as a monomer and binds two zinc ions per subunit. Recombinant human HAGH protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Hydroxyacylglutathione hydrolase, GLO, GLX2, Glyoxalase II, HAGH1. NCBI no.: NP_001035517

Poids moléculaire: 31.4 kDa (284aa), confirmed by MALDI-TOF