SPOP-B Protein (AA 1-374) (His tag)

N° du produit ABIN667901

Détail du produit

Antigène: SPOP-B (Speckle-Type POZ Protein (SPOP-B))

Type de proteíne: Recombinant

Attributs du protein: AA 1-374

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SPOP-B protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: SPOP, 1-374aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 50% glycerol, 0.2M NaCl, 2mM EDTA

Stock: 4 °C

Détail du antigène

Antigène: SPOP-B (Speckle-Type POZ Protein (SPOP-B))

Autre désignation: SPOP (SPOP-B Produits)

Synonymes: BTBD32 Protein, TEF2 Protein, AI315626 Protein, Pcif1 Protein, zgc:64140 Protein, spop Protein, tef2 Protein, speckle type BTB/POZ protein Protein, speckle-type POZ protein Protein, speckle type POZ protein S homeolog Protein, SPOP Protein, Spop Protein, spop Protein, spop.S Protein

Sujet: SPOP (speckle-type POZ protein), also known as TEF2, is a member of the Tdpoz family containing one N-terminal MATH (Meprin and TRAF homology) domain and one C-terminal BTB/POZ domain. This protein inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex. Through an interaction with CUL-3, SPOP is involved in ubiquitinylation and protein degradation. Recombinant human SPOP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Speckle-type POZ protein, TEF2. NCBI no.: NP_001007231

Poids moléculaire: 44.3kDa (394aa), confirmed by MALDI-TOF