CTDSP1 Protein (AA 1-260) (His tag)

N° du produit ABIN667902

Détail du produit

Antigène: CTDSP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1))

Type de proteíne: Recombinant

Attributs du protein: AA 1-260

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CTDSP1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: CTDSP1, 1-260aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl

Stock: 4 °C

Détail du antigène

Antigène: CTDSP1 (CTD (Carboxy-terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 1 (CTDSP1))

Autre désignation: CTDSP1 (CTDSP1 Produits)

Synonymes: CTDSP1 Protein, NIF3 Protein, NLI-IF Protein, NLIIF Protein, SCP1 Protein, fj83f12 Protein, im:7141428 Protein, wu:fj83f12 Protein, zgc:113169 Protein, GIP Protein, Nif3 Protein, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 Protein, CTD small phosphatase 1 Protein, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 Protein, CTDSP1 Protein, Ctdsp1 Protein, ctdsp1 Protein, HCAG_04820 Protein, CTRG_06220 Protein

Sujet: Carboxy-terminal domain, RNA polymerase II, polypeptide A phosphatase 1, also known as CTDSP1, is a class 2C phosphatase with activity dependent on the conserved DxD motif. CTDSP1 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Also it negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recombinant human CTDSP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Carboxy-terminal domain, RNA polymerase II, polypeptide A phosphatase 1, NLIIF, SCP1, NIF3. NCBI no.: NP_872580

Poids moléculaire: 31.2 kDa (280aa), confirmed by MALDI-TOF