BST2 Protein (AA 50-161) (His tag)

N° du produit ABIN667927

Détail du produit

Antigène: BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

Type de proteíne: Recombinant

Attributs du protein: AA 50-161

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette BST2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: BST2, 50-161aa, Human, His tag, E.coli

Pureté: > 80 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Stock: 4 °C

Détail du antigène

Antigène: BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

Autre désignation: BST2 (BST2 Produits)

Synonymes: BST2 Protein, CD317 Protein, TETHERIN Protein, 2310015I10Rik Protein, Bst-2 Protein, C87040 Protein, DAMP-1 Protein, GREG Protein, Damp1 Protein, bone marrow stromal cell antigen 2 Protein, bone marrow stromal antigen 2 Protein, BST2 Protein, LOC618737 Protein, Bst2 Protein

Sujet: BST2, also known as bone marrow stromal antigen 2, is involved in the growth and development of B-cells. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. Initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, tetherin has also been shown to inhibit the release of other viruses such as the Lassa and Marburg virions. Also, this protein may play a role in B-cell activation in rheumatoid arthritis. Recombinant human BST2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Bone marrow stromal antigen 2, HM1.24 antigen, Tetherin, CD317. NCBI no.: NP_004326

Poids moléculaire: 14.8 kDa (133aa), confirmed by MALDI-TOF

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response