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BST2 Protein (AA 49-161) (His tag)

BST2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
N° du produit ABIN7273992
  • Antigène Voir toutes BST2 Protéines
    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 49-161
    Origine
    • 10
    • 5
    • 2
    • 1
    Humain
    Source
    • 5
    • 5
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette BST2 protéine est marqué à la His tag.
    Fonction
    Human BST2 Protein
    Séquence
    Asn49-Ser161
    Attributs du produit
    Recombinant Human BST2 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Asn49-Ser161.
    Pureté
    > 95 % as determined by Tris-Bis PAGE
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human BST2, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-BST2 Antibody, hFc Tag with the EC50 of 15.9ng/ml determined by ELISA. See testing image for detail.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
    Autre désignation
    BST2 (BST2 Produits)
    Synonymes
    BST2 Protein, CD317 Protein, TETHERIN Protein, 2310015I10Rik Protein, Bst-2 Protein, C87040 Protein, DAMP-1 Protein, GREG Protein, Damp1 Protein, bone marrow stromal cell antigen 2 Protein, bone marrow stromal antigen 2 Protein, BST2 Protein, LOC618737 Protein, Bst2 Protein
    Sujet
    Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune response. BST2 expression was significantly increased during porcine epidemic diarrhea virus (PEDV) infection of Vero cells by IRF1 targeting its promoter. Both the BST2 and N protein interacted with the E3 ubiquitin ligase MARCHF8/MARCH8 and the cargo receptor.
    Poids moléculaire
    14.5 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.
    Pathways
    Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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