PTPMT1 Protein (AA 28-201) (His tag)

N° du produit ABIN667999

Détail du produit

Antigène: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Type de proteíne: Recombinant

Attributs du protein: AA 28-201

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PTPMT1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PTPMT1, 28-201 aa , Human, His tag E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl.

Stock: 4 °C

Détail du antigène

Antigène: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Autre désignation: PTPMT1 (PTPMT1 Produits)

Synonymes: im:7137979 Protein, zgc:158719 Protein, DUSP23 Protein, MOSP Protein, PLIP Protein, 1110001D10Rik Protein, 2810004N20Rik Protein, Plip Protein, protein tyrosine phosphatase, mitochondrial 1 Protein, PTPMT1 Protein, ptpmt1 Protein, Ptpmt1 Protein

Sujet: PTPMT1 (protein tyrosine phosphatase mitochondrial 1), also known as MOSP or PLIP (phosphoinositide lipid phosphatase) and previously known as DUSP23, is a widely expressed PTP membrane protein with high expression levels in pancreatic beta cells. This protein exclusively localizes to the matrix face of the inner membrane of the mitochondrion. It is responsible for dephosphorylating mitochondrial proteins and therefore plays a significant role in the production of ATP and secretion of insulin. For its substrate, PTPMT1 displays a specific preference for the lipid signaling molecule phosphatidylinositol 5-phosphate. Recombinant human PTPMT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Protein tyrosine phosphatase, mitochondrial 1, DUSP23, FLJ46081, MOSP, PLIP, PNAS-129. NCBI no.: NP_783859

Poids moléculaire: 22.6 kDa (199aa), confirmed by MALDI-TOF

Pathways: Inositol Metabolic Process