ATG4B Protein (AA 1-393) (His tag)

N° du produit ABIN668029

Détail du produit

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Type de proteíne: Recombinant

Attributs du protein: AA 1-393

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ATG4B protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: ATG4B, 1-393aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT, 0.1mM PMSF

Stock: 4 °C

Détail du antigène

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Autre désignation: ATG4B (ATG4B Produits)

Synonymes: apg4b Protein, APG4B Protein, AUTL1 Protein, 2510009N07Rik Protein, AW048066 Protein, Apg4b Protein, Atg4bl Protein, Autl1 Protein, Aut2b2 Protein, autophagy related 4B cysteine peptidase Protein, autophagy-related 4b Protein, Peptidase family C54 protein Protein, cysteine protease ATG4B Protein, ATG4 autophagy related 4 homolog B (S. cerevisiae) Protein, autophagy related 4B, cysteine peptidase Protein, autophagy related 4B, cysteine peptidase L homeolog Protein, ATG4B Protein, Atg4b Protein, AT3G59950 Protein, Tsp_08582 Protein, Tsp_11599 Protein, atg4b Protein, atg4b.L Protein

Sujet: ATG4B, also known as cysteine protease ATG4B, is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Recombinant human ATG4B protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: AUTL1, Autophagin-1. NCBI no.: AAH00719

Poids moléculaire: 45.4 kDa (401aa) confirmed by MALDI-TOF

Pathways: Autophagy