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IL17C Protein (AA 19-197) (His tag)

IL17C Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
N° du produit ABIN6952297
  • Antigène Voir toutes IL17C Protéines
    IL17C (Interleukin 17C (IL17C))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 19-197
    Origine
    • 9
    • 4
    • 2
    • 1
    Humain
    Source
    • 6
    • 6
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette IL17C protéine est marqué à la His tag.
    Pureté
    >95 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL17C Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Stock
    -20 °C
  • Antigène
    IL17C (Interleukin 17C (IL17C))
    Autre désignation
    IL-17C (IL17C Produits)
    Synonymes
    IL17C Protein, il17-3 Protein, CX2 Protein, IL-17C Protein, IL-21 Protein, interleukin 17C Protein, interleukin 17c Protein, IL17C Protein, il17c Protein, Il17c Protein
    Sujet
    Interleukin-17C(IL-17C) is a glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL-17C binds to IL-17 RE with high affinity and to IL-17 RA with low affinity, binds to a heterodimer formed by IL17RA and IL17RE. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes.
    Poids moléculaire
    21.6 kDa
    NCBI Accession
    NP_037410
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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