CCR9 Protein (Fc Tag)

N° du produit ABIN6964146

Détail du produit

Antigène: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CCR9 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human CCR9 with C-terminal human Fc tag

Specificité: CCR9 (Met1-Ser48) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Agent conservateur: Without preservative

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Autre désignation: CCR9 (CCR9 Produits)

Synonymes: CC-CKR-9 Protein, CDw199 Protein, GPR-9-6 Protein, GPR28 Protein, A130091K22Rik Protein, Cmkbr10 Protein, C-C motif chemokine receptor 9 Protein, chemokine (C-C motif) receptor 9 Protein, CCR9 Protein, Ccr9 Protein

Sujet: Synonymes: CC-CKR-9, CDw199, GPR-9-6, GPR28
Description: The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: predicted molecular mass of 31.6 kDa after removal of the signal peptide. The apparent molecular mass of CCR9-hFc is 35-55 kDa due to glycosylation.

UniProt: P51686