CCR9 Protéine

N° du produit ABIN7491572

Détail du produit

Antigène: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Type de proteíne: Synthetic

Origine: Humain

Source: HEK-293 Cells

Fonction: Human CCR9 full length protein-synthetic nanodisc

Attributs du produit: Full Length Transmembrane Proteins (synthetic Nanodisc)

Information d'application

Indications d'application:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Commentaires:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Autre désignation: CCR9 (CCR9 Produits)

Synonymes: CC-CKR-9 Protein, CDw199 Protein, GPR-9-6 Protein, GPR28 Protein, A130091K22Rik Protein, Cmkbr10 Protein, C-C motif chemokine receptor 9 Protein, chemokine (C-C motif) receptor 9 Protein, CCR9 Protein, Ccr9 Protein

Sujet: CC-CKR-9, CDw199, GPR-9-6, GPR28
Description: The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]

Poids moléculaire: The human full length CCR9 protein has a MW of 42.02 kDa

UniProt: P51686