CD4 Protein (CD4) (Fc Tag)

N° du produit ABIN6964180

Cette protéine Recombinant CD4 est exprimée dans HEK-293 Cells.

Aperçu rapide pour CD4 Protein (CD4) (Fc Tag) (ABIN6964180)

Antigène: CD4

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Détail du produit

Purification/Conjugué: Cette CD4 protéine est marqué à la Fc Tag.

Séquence: CD4(Lys26-Trp390)+hFc(Glu99-Ala330)

Attributs du produit: Tagged Protein: C-Human Fc tag

Purification: affinity purification

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Agent conservateur: Without preservative

Stock: -80 °C

Stockage commentaire: Store at -80°C for 12 months (Avoid repeated freezing and thawing)

Date de péremption: 12 months

Détail du antigène

Antigène: CD4

Autre désignation: CD4

Sujet: Synonymes: CD4,CD4mut,LEU3
Description: This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Poids moléculaire: 65.67 kDa

UniProt: P01730

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events