IFNAR2 Protein (Fc Tag)

N° du produit ABIN6964274

Détail du produit

Antigène: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IFNAR2 protéine est marqué à la Fc Tag.

Fonction: Recombinant human IFNAR2 protein with C-terminal human Fc tag

Specificité: IFNAR2 (Ile27-Lys243) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Agent conservateur: Without preservative

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Autre désignation: IFNAR2 (IFNAR2 Produits)

Synonymes: AI747302 Protein, Ifnar-2 Protein, IFN-R Protein, IFN-alpha-REC Protein, IFNABR Protein, IFNARB Protein, IFN-R-2 Protein, IFNBR Protein, interferon alpha and beta receptor subunit 2 Protein, interferon (alpha and beta) receptor 2 Protein, IFNAR2 Protein, Ifnar2 Protein

Sujet: Synonymes: IFN-alpha-REC, IFN-R, IFNABR, IFNARB, IMD45
Description: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 50.9 kDa after removal of the signal peptide. The apparent molecular mass of IFNAR2-hFc is 55-70 kDa due to glycosylation.

UniProt: P48551

Pathways: Signalistation JAK/STAT, Hepatitis C