PVRIG Protein (AA 41-171) (Fc Tag,AVI tag,Biotin)

N° du produit ABIN6973209

Détail du produit

Antigène: PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 41-171

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PVRIG protéine est marqué à la Fc Tag,AVI tag,Biotin.

Specificité: Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

Attributs du produit: Biotinylated Human PVRIG Protein, Fc,Avitag™ (HPLC verified)

Pureté: >90 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: HPLC verified

Commentaires:

Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS,  pH 7.4

Stock: -20 °C

Détail du antigène

Antigène: PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))

Autre désignation: PVRIG (PVRIG Produits)

Synonymes: C7orf15 Protein, PVR related immunoglobulin domain containing Protein, PVRIG Protein

Sujet: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34  kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3 % similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

Poids moléculaire: 41.9 kDa

NCBI Accession: NP_076975