Origine: Rabies Virus
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % , based on SDS PAGE
Imm, ELISA, WB
Restrictions
For Research Use only
Format
Lyophilized
Buffer
40 mM PB, 500 mM NaCl, pH 7.4
Stock
-20 °C
Antigène
Nucleoprotein
Autre désignation
Nucleocapsid protein
Synonymes
NP Protein, Protein N Protein, nucleocapsid protein Protein, N Protein
Classe de substances
Influenza Protein
Sujet
Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology, 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.