SARS-CoV-2 Spike S1 Protein (B.1.1.7 - alpha) (Fc Tag)

N° du produit ABIN6992403

Détail du produit

Antigène: SARS-CoV-2 Spike S1

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: B.1.1.7 - alpha

Origine: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha

Source: HEK-293 Cells

Purification/Conjugué: Cette SARS-CoV-2 Spike S1 protéine est marqué à la Fc Tag.

Fonction: SARS-CoV-2 S1 protein (HV69-70del, Y144del, N501Y, A570D, D614G, P681H), Fc Tag

Séquence: AA 16-685

Attributs du produit: SARS-CoV-2 S1 protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). The mutations (HV69-70del, Y144del, N501Y, A570D, D614G, P681H) were identified in the SARS-CoV-2 variant (known as B.1.1.7, 20B/501Y.V1 or VOC 202012/01) which emerged in the United Kindom.

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, 0.2 M Arginine, 150 mM NaCl, pH 7.5

Stock: -20 °C

Détail du antigène

Antigène: SARS-CoV-2 Spike S1

Autre désignation: SARS-CoV-2 S1 protein (SARS-CoV-2 Spike S1 Produits)

Synonymes: E2 Protein, Surface Glycoprotein Protein, S Protein

Classe de substances: Viral Protein

Sujet: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Poids moléculaire: 101.1 kDa