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Neuropilin 1 Protein (NRP1) (AA 22-856) (His tag)

NRP1 Origine: Souris Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
N° du produit ABIN6992419
  • Antigène Voir toutes Neuropilin 1 (NRP1) Protéines
    Neuropilin 1 (NRP1)
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 22-856
    Origine
    • 17
    • 7
    • 5
    • 1
    Souris
    Source
    • 11
    • 11
    • 4
    • 3
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Neuropilin 1 protéine est marqué à la His tag.
    Fonction
    Mouse Neuropilin-1 / NRP1 / CD304 Protein, His Tag
    Pureté
    >90 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product NRP1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Stock
    -20 °C
  • Antigène
    Neuropilin 1 (NRP1)
    Autre désignation
    Neuropilin-1 (NRP1 Produits)
    Synonymes
    NRP1 Protein, cd304 Protein, neuropilin Protein, np-1 Protein, npn-1 Protein, nrp Protein, nrp-1 Protein, vegf165r Protein, BDCA4 Protein, CD304 Protein, NP1 Protein, NRP Protein, VEGF165R Protein, C530029I03 Protein, NP-1 Protein, NPN-1 Protein, Npn1 Protein, Nrp Protein, neuropilin 1 Protein, neuropilin 1 L homeolog Protein, NRP1 Protein, nrp1 Protein, Nrp1 Protein, nrp1.L Protein
    Sujet
    Neuropilin-1 (NRP1) is also known as Vascular endothelial cell growth factor 165 receptor (VEGF165R), CD antigen CD304, which belongs to the neuropilin family. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.
    Poids moléculaire
    95.5 kDa
    NCBI Accession
    NP_032763
    Pathways
    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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