MADCAM1 Protein (AA 19-333) (Fc Tag)
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- Antigène Voir toutes MADCAM1 Protéines
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 19-333
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette MADCAM1 protéine est marqué à la Fc Tag.
- Fonction
- Human MAdCAM-1 Protein, Fc Tag (MALS verified)
- Pureté
- >95 % as determined by reduced SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MADCAM1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
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- Antigène
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- Autre désignation
- MAdCAM-1 (MADCAM1 Produits)
- Synonymes
- MACAM1 Protein, AV211525 Protein, mucosal vascular addressin cell adhesion molecule 1 Protein, MADCAM1 Protein, Madcam1 Protein
- Sujet
- The mucosal addressin cell adhesion molecule-1 (MAdCAM-1) takes a key role in the endothelial adhesion and migration of lymphocytes to sites of inflammation in inflammatory disease. In vitro and in vivo data indicate that blockade of the adhesion molecule mucosal address in cell adhesion molecule (MAdCAM) pathway decreases leukocyte homing to the gut by inhibiting the interaction between MAdCAM and its ligand the α4β7 integrin expressed on lymphocytes.
- Poids moléculaire
- 59.6 kDa
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