MARCO Protein (AA 79-520) (His tag)
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- Antigène Voir toutes MARCO Protéines
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 79-520
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette MARCO protéine est marqué à la His tag.
- Fonction
- Human MARCO Protein, His Tag
- Pureté
- >90 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MARCO Protéine
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Macrophage Receptor with Collagenous Structure (MARCO) (AA 70-518) protein (His tag)
MARCO Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Macrophage Receptor with Collagenous Structure (MARCO) (AA 405-520) protein (His tag)MARCO Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Macrophage Receptor with Collagenous Structure (MARCO) (AA 65-520) protein (His tag)Crystallography grade MARCO Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Macrophage Receptor with Collagenous Structure (MARCO) (AA 70-518) protein (His tag)Crystallography grade MARCO Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Macrophage Receptor with Collagenous Structure (MARCO) (AA 1-520) protein (Strep Tag)Crystallography grade MARCO Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Macrophage Receptor with Collagenous Structure (MARCO) (AA 1-518) protein (Strep Tag)Crystallography grade MARCO Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
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- Antigène
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
- Autre désignation
- MARCO (MARCO Produits)
- Synonymes
- AI323439 Protein, Ly112 Protein, Scara2 Protein, SCARA2 Protein, macrophage receptor with collagenous structure Protein, MARCO Protein, Marco Protein
- Sujet
- MARCO is also known as Scavenger receptor class A member 2 and SCARA2. Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria. Also plays a role in binding of unopsonized particles by alveolar macrophages. Binds to the secretoglobin SCGB3A2. MARCO ligation promotes the production of inflammatory mediators by macrophages. MARCO mediated internalization of some ligands prevents their activation of cell surface TLR4 but enables their activation of intracellular TLR3. MARCO contributes to the clearance of apoptotic cells and inhaled bacteria, mast cell mediated silicosis, and the amelioration of allergen or ozone induced lung inflammation. It is required for the organization of the splenic marginal zone and the interaction of splenic macrophages and B cells.
- Poids moléculaire
- 45.9 kDa
- Pathways
- Activation of Innate immune Response
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