MICA Protein (AA 24-308) (Fc Tag)
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- Antigène Voir toutes MICA Protéines
- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 24-308
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette MICA protéine est marqué à la Fc Tag.
- Attributs du produit
- Human MICA Protein, Fc Tag (MALS verified)
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MICA Protéine
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- Indications d'application
- MALS verified
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
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- Antigène
- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
- Autre désignation
- MICA (MICA Produits)
- Synonymes
- MIC-A Protein, PERB11.1 Protein, MHC class I polypeptide-related sequence A Protein, MICA Protein
- Sujet
- MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.
- Poids moléculaire
- 59.3 kDa
- Pathways
- Activation of Innate immune Response, Transition Metal Ion Homeostasis
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