ZNRF3 Protein (AA 56-219) (His tag)

N° du produit ABIN7013661

Détail du produit

Antigène: ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))

Type de proteíne: Recombinant

Attributs du protein: AA 56-219

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ZNRF3 protéine est marqué à la His tag.

Séquence: AA 56-219

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: MALS verified

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Détail du antigène

Antigène: ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))

Autre désignation: ZNRF3 (ZNRF3 Produits)

Synonymes: BK747E2.3 Protein, RNF203 Protein, AA591877 Protein, BC019575 Protein, Gm1167 Protein, zinc and ring finger 3 Protein, Znrf3 Protein, ZNRF3 Protein

Sujet: The transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) is a negative feedback regulator of Wnt signalling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signalling by promoting the turnover of frizzled and LRP6 and acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway.

Poids moléculaire: 19.7 kDa

NCBI Accession: NP_001193927

Pathways: Signalisation WNT