SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (B.1.1.529 - Omicron) (His tag)

N° du produit ABIN7041441

Détail du produit

Antigène: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

Type de proteíne: Recombinant

Attributs du protein: B.1.1.529 - Omicron

Origine: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron

Source: HEK-293 Cells

Purification/Conjugué: Cette SARS-CoV-2 Nucleocapsid protéine est marqué à la His tag.

Application: SDS-PAGE (SDS), ELISA

Fonction: SARS-CoV-2 Nucleocapsid protein, His Tag (B.1.1.529/Omicron)

Attributs du produit: SARS-CoV-2 Nucleocapsid protein, His Tag (B.1.1.529/Omicron) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1(P13L, ERS31-33del, R203K, G204R). The mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: B.1.1.529; GISAID clade: GR/484A; Nextstrain clade: 21K). Predicted N-terminus: Met 1

Pureté: > 95% as determined by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C/-80 °C

Stockage commentaire: For long term storage, the product should be stored at lyophilized state at -20°C or lower.This product is stable after storage at:
4-8°C for 12 months in lyophilized state,
-70°C for 3 months under sterile conditions after reconstitution.

Date de péremption: 12 monts

Détail du antigène

Antigène: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

Autre désignation: SARS-CoV-2 N protein (SARS-CoV-2 N Produits)

Synonymes: nucleocapsid phosphoprotein Protein, N Protein

Classe de substances: Viral Protein

Sujet: Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

Poids moléculaire: 47.3 kDa