FOLR2 Protein (mFc Tag)

N° du produit ABIN7092685

Détail du produit

Antigène: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette FOLR2 protéine est marqué à la mFc Tag.

Fonction: Recombinant human FOLR2 protein with C-terminal mouse Fc tag

Specificité: FOLR2 (Thr17-His228) mFc (Pro99-Lys330)

Attributs du produit: Extracellular Domain Protein

Purification: affinity purification

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Autre désignation: FOLR2 (FOLR2 Produits)

Synonymes: FOLR2 Protein, BETA-HFR Protein, FBP Protein, FBP/PL-1 Protein, FR-BETA Protein, FR-P3 Protein, FBP2 Protein, Folbp-2 Protein, Folbp2 Protein, folate receptor 1 Protein, folate receptor beta Protein, folate receptor 2 (fetal) Protein, FOLR1 Protein, FOLR2 Protein, Folr2 Protein

Sujet: Synonymes: BETA-HFR
Description: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68 % and 79 % sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 50.7 kDa after removal of the signal peptide.The apparent molecular mass of FOLR2-mFc is 35-55 kDa due to glycosylation.

UniProt: P14207

Pathways: Dicarboxylic Acid Transport