FOLR2 Protein (AA 17-228) (His tag)

N° du produit ABIN7274664

Détail du produit

Antigène: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Type de proteíne: Recombinant

Attributs du protein: AA 17-228

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette FOLR2 protéine est marqué à la His tag.

Fonction: Human FOLR2 Protein

Séquence: Thr17-Met228

Attributs du produit: Recombinant Human FOLR2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr17-Met228.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human FOLR2, His Tag at 0.2μg/ml (100μl/well) on the plate. Dose response curve for Anti-FOLR2 Antibody, hFc Tag with the EC50 of 11.7ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Autre désignation: FOLR2 (FOLR2 Produits)

Synonymes: FOLR2 Protein, BETA-HFR Protein, FBP Protein, FBP/PL-1 Protein, FR-BETA Protein, FR-P3 Protein, FBP2 Protein, Folbp-2 Protein, Folbp2 Protein, folate receptor 1 Protein, folate receptor beta Protein, folate receptor 2 (fetal) Protein, FOLR1 Protein, FOLR2 Protein, Folr2 Protein

Sujet: FOLR1 and FOLR2 are equipped with cellular glycosylphosphatidylinositol (GPI) anchors. FOLR1 is secreted from epithelia with or without a micelle-encapsulated GPI-anchor into milk and other body fluids/secretions, e.g. semen where its interaction with spermatozoa indicates a role in male fertility. FOLR1 and FOLR2 serve as serum biomarkers of various diseases. FOLR3 possesses no GPI-anchor and originates from secretory granules of neutrophil granulocytes, its concentration in serum correlates to the FOLR3 content in leukocytes and rises with increased leukocyte counts (infection, malignancy and pregnancy).

Poids moléculaire: 25.5 kDa. Due to glycosylation, the protein migrates to 30-38 kDa based on Tris-Bis PAGE result.

UniProt: P14207

Pathways: Dicarboxylic Acid Transport