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CLEC5A Protein (His tag)

MALS verified CLEC5A Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
N° du produit ABIN7121255
  • Antigène Voir toutes CLEC5A Protéines
    CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
    Type de proteíne
    Recombinant
    Origine
    • 4
    • 3
    • 1
    • 1
    Humain
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette CLEC5A protéine est marqué à la His tag.
    Fonction
    Human CLEC5A / MDL-1 Protein, His Tag (MALS & SPR verified)
    Séquence
    Pro 28 - Lys 188
    Attributs du produit
    Human CLEC5A, His Tag (CLA-H5243) is expressed from human 293 cells (HEK293). It contains AA Pro 28 - Lys 188 (Accession # Q9NY25-1).
    Pureté
    >95 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Classe de qualité
    MALS verified
    Top Product
    Discover our top product CLEC5A Protéine
  • Indications d'application
    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 20.3 kDa. The protein migrates as 60-66 kDa under reducing (R) condition due to glycosylation.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Stock
    -20 °C
    Stockage commentaire
    -20°C
  • Antigène
    CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
    Autre désignation
    CLEC5A / MDL-1 (CLEC5A Produits)
    Synonymes
    CLECSF5 Protein, MDL-1 Protein, MDL1 Protein, Clecsf5 Protein, Ly100 Protein, Mdl1 Protein, C-type lectin domain containing 5A Protein, C-type lectin domain family 5, member a Protein, CLEC5A Protein, Clec5a Protein
    Sujet
    Synonyms: CLEC5A,CLECSF5,superfamilymember 5,C-type lectin domain family 5, member A,MDL1,MDL-1,DAP12-associating lectin 1,
    Description: CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.CLEC5A is expressed on monocytes, macrophages, and neutrophils. Its expression is up-regulated on monocytes in rheumatoid arthritis. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
    Poids moléculaire
    20.3 kDa
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