SARS-CoV-2 Spike S1 Protein (BA.3 - Omicron) (His tag)

N° du produit ABIN7121372

Détail du produit

Antigène: SARS-CoV-2 Spike S1

Type de proteíne: Recombinant

Attributs du protein: BA.3 - Omicron

Origine: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron

Source: HEK-293 Cells

Purification/Conjugué: Cette SARS-CoV-2 Spike S1 protéine est marqué à la His tag.

Fonction: SARS-CoV-2 Spike S1, His Tag (BA.3/Omicron)

Séquence: Val 16 - Arg 685

Specificité: SARS-CoV-2 Spike S1 (BA.3/Omicron)

Attributs du produit: SARS-CoV-2 Spike S1, His Tag (BA.3/Omicron) (S1N-C52Hq) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1 (A67V,H69del,V70del,T95I,G142D,V143del,Y144del,Y145del,N211del,L212I,G339D,S371F,S373P,S375F,D405N,K417N,N440K,G446S,S477N,T478K,E484A,Q493R,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.3, GISAID clade: GRA, Nextstrain clade: 21M).

Pureté: >90 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.5 kDa. The protein migrates as kDa under reducing (R) condition due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: SARS-CoV-2 Spike S1

Abstract: SARS-CoV-2 Spike S1 Produits

Synonymes: E2 Protein, Surface Glycoprotein Protein, S Protein

Classe de substances: Viral Protein

Sujet: Synonyms: Spike,S1 protein,Spike glycoprotein Subunit1,S glycoprotein Subunit1,Spike protein S1,
Description: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Poids moléculaire: 76.5 kDa