IL-2 R beta & IL-2 R gamma protein (Fc Tag)

N° du produit ABIN7121423

Détail du produit

Antigène: IL-2 R beta & IL-2 R gamma

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Fc Tag

Fonction: Mouse IL-2 R beta&IL-2 R gamma Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

Séquence: Ala 27 - Glu 240 (IL-2RB) & Trp 23 - Ala 263 (IL-2RG)

Attributs du produit: Mouse IL-2RB&IL-2RG Heterodimer Protein, Fc Tag&Fc Tag (ILG-M5254) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Glu 240 (IL-2RB) & Trp 23 - Ala 263 (IL-2RG) (Accession # P16297-1 (IL-2RB) & P34902-1 (IL-2RG).

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Classe de qualité: MALS verified

Information d'application

Indications d'application: Mouse IL-2RB&IL-2RG Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of IL-2RB and IL-2RG, has a calculated MW of 51.5 kDa (IL-2RB) and 54.5 kDa (IL-2RG). Subunit IL-2RB is fused with a human IgG1 Fc tag at the C-terminus and subunit IL-2RG is fused with a human IgG1 Fc tag at the C-terminus. The protein migrates as 65-100 kDa under reducing (R) condition due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: IL-2 R beta & IL-2 R gamma

Autre désignation: IL-2 R beta&IL-2 R gamma

Sujet: Synonyms: IL-2 R beta & IL-2 R gamma,IL-2RB & IL-2RG,
Description: Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

Poids moléculaire: 51.5 kDa & 54.5 kDa