SOSTDC1 Protein (Fc Tag)
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- Antigène Voir toutes SOSTDC1 Protéines
- SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette SOSTDC1 protéine est marqué à la Fc Tag.
- Fonction
- Human USAG-1 Protein, Fc Tag
- Séquence
- Phe 24 - Ser 206
- Attributs du produit
- Human USAG-1, Fc Tag (US1-H5254) is expressed from human 293 cells (HEK293). It contains AA Phe 24 - Ser 206 (Accession # Q6X4U4-1).
- Pureté
- >90 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SOSTDC1 Protéine
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- Indications d'application
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 47.2 kDa. The protein migrates as 45-65 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Stock
- -20 °C
- Stockage commentaire
- -20°C
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- Antigène
- SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))
- Autre désignation
- USAG-1 (SOSTDC1 Produits)
- Synonymes
- SOSTDC1 Protein, zgc:110293 Protein, DKFZp469J0531 Protein, Usag1 Protein, ECTODIN Protein, USAG1 Protein, 0610006G05Rik Protein, Sostl Protein, USAG-1 Protein, Wise Protein, ectodin Protein, WISE Protein, sclerostin domain containing 1 Protein, sclerostin domain containing 1a Protein, SOSTDC1 Protein, sostdc1a Protein, Sostdc1 Protein
- Sujet
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Synonyms: Uterine sensitization-associated gene 1 protein,
Description: USAG1 (uterine sensitization associated gene 1), also known asSOSTDC1 (sclerostin domain-containing 1), Ectodin, is a secreted protein with a glycosylated N-terminus that contains a C-terminal cysteine knot domain. This C-terminal cysteine knot domain is present in numerous growth factors, including TGFβ, NGF, PDGF, vWF, NDP, and mucin-2, and involved in dimerization, receptor binding, and signal transduction. SOSTDC1 negatively regulates BMP signaling during cellular proliferation, differentiation, and apoptosis in several biological processes (such as dentary morphogenesis, embryo implantation in the endo-metrium, and healing of bone fractures) [8]. In addition, SOSTDC1 might also involve cancer development processes through the regulation of the Wnt pathway. - Poids moléculaire
- 47.2 kDa
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