KIR3DL3 Protein (Fc Tag)

N° du produit ABIN7121540

Détail du produit

Antigène: KIR3DL3 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 3 (KIR3DL3))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette KIR3DL3 protéine est marqué à la Fc Tag.

Fonction: Human KIR3DL3 / CD158z Protein, Fc Tag

Séquence: Gln 26 - Leu 322

Attributs du produit: Human KIR3DL3, Fc Tag (KI3-H5259) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Leu 322 (Accession # Q8N743-1).

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 58.7 kDa. The protein migrates as 66 kDa under reducing (R) condition due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: KIR3DL3 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 3 (KIR3DL3))

Autre désignation: KIR3DL3 / CD158z (KIR3DL3 Produits)

Synonymes: CD158Z Protein, KIR3DL7 Protein, KIR44 Protein, KIRC1 Protein, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3 Protein, KIR3DL3 Protein

Sujet: Synonyms: Killer cell immunoglobulin-like receptor 3DL3,CD158 antigen-like family member Z,Killer cell inhibitory receptor 1,CD158z,KIR3DL3,KIR3DL7,KIRC1,
Description: the inhibitory KIR surface receptors possessing three extracellular immunoglobin (Ig) domains (3D) and only one inhibitory motif within the long cytoplasmic domain (L) due to a premature stop codon. Moreover, exon 6 of KIR3DL3 encoding the stem part of the receptor is also absent, which differs from other inhibitory KIRs. Understanding the function of KIR3DL3 is further complicated by the unknown identity of the specific ligand, but its importance is highlighted by its presence in all human KIR haplotypes with 120 distinct polymorphic alleles of the coding sequence [

Poids moléculaire: 58.7 kDa