ART4 Protein (His tag)

N° du produit ABIN7321097

Détail du produit

Antigène: ART4 (ADP-Ribosyltransferase 4 (Dombrock Blood Group) (ART4))

Type de proteíne: Recombinant

Origine: Rat

Source: HEK-293 Cells

Purification/Conjugué: Cette ART4 protéine est marqué à la His tag.

Fonction: Recombinant Rat ART4 Protein (His Tag)

Séquence: Met1-Lys269

Attributs du produit: A DNA sequence encoding the rat ART4 (Met1-Lys269) was expressed with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: ART4 (ADP-Ribosyltransferase 4 (Dombrock Blood Group) (ART4))

Autre désignation: ART4 (ART4 Produits)

Synonymes: ARTC4 Protein, CD297 Protein, DO Protein, DOK1 Protein, ATR4 Protein, 4432404K01Rik Protein, Dombrock Protein, ADP-ribosyltransferase 4 (Dombrock blood group) Protein, ADP-ribosyltransferase 4 Protein, ART4 Protein, Art4 Protein

Sujet:

Background: ADP-ribosyltransferase 4 (Dombrock blood group), also known as Mono-ADP-ribosyltransferase 4(ART4), Dombrock blood group carrier molecule and CD297, is a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. ART4 could be detected on HEL cells and erythrocytes by FACS analysis while it was absent from activated monocytes, despite the presence of ART4 mRNA in these cells. ART is also known as the carrier of the Dombrock blood group alloantigens (Do) which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane.

Synonym: ART4

Poids moléculaire: 28.4 kDa

NCBI Accession: NP_001166980