APBA3 Protein (His tag)

N° du produit ABIN7318152

Détail du produit

Antigène: APBA3 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette APBA3 protéine est marqué à la His tag.

Fonction: Recombinant Human APBA3 Protein (His Tag)

Séquence: Met 1-Leu138

Attributs du produit: Recombinant Human Amyloid beta A4 Precursor Protein-Binding Family A Member 3 is produced by our E.coli expression system and the target gene encoding Met1-Leu138 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB ,150 mM NaCl, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: APBA3 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 3 (APBA3))

Autre désignation: APBA3 (APBA3 Produits)

Synonymes: AW208791 Protein, Mint-3 Protein, X11gamma Protein, lin-10 Protein, mint3 Protein, MGC:15815 Protein, X11L2 Protein, Mint3 Protein, amyloid beta precursor protein binding family A member 3 Protein, amyloid beta (A4) precursor protein-binding, family A, member 3 Protein, APBA3 Protein, Apba3 Protein

Sujet:

Background: Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amyloid protein (APP) in vivo and may modulate processing of the β-amyloid precursor protein (APP) and hence formation of β-APP.

Synonym: Amyloid Beta A4 Precursor Protein-Binding Family A Member 3, Adapter protein X11Gamma, Neuron-Specific X11L2 Protein, Neuronal Munc18-1-Interacting Protein 3, Mint-3, APBA3, MINT3, X11L2

Poids moléculaire: 15.5 kDa

UniProt: O96018