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Biglycan Protein (BGN) (His tag)

BGN Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318199
  • Antigène Voir toutes Biglycan (BGN) Protéines
    Biglycan (BGN)
    Type de proteíne
    Recombinant
    Origine
    • 9
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette Biglycan protéine est marqué à la His tag.
    Fonction
    Recombinant Human Biglycan/BGN Protein (His Tag)
    Séquence
    Glu20-Lys368
    Attributs du produit
    Recombinant Human Biglycan is produced by our Mammalian expression system and the target gene encoding Glu20-Lys368 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product BGN Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    Biglycan (BGN)
    Autre désignation
    Biglycan/BGN (BGN Produits)
    Synonymes
    DSPG1 Protein, PG-S1 Protein, PGI Protein, SLRR1A Protein, BG Protein, BSPG1 Protein, bgn Protein, zgc:91989 Protein, dspg1 Protein, pg-s1 Protein, slrr1a Protein, xbgn Protein, BGN Protein, zgc:77123 Protein, DKFZp468I2427 Protein, biglycan Protein, biglycan L homeolog Protein, biglycan a Protein, biglycan S homeolog Protein, biglycan b Protein, BGN Protein, Bgn Protein, bgn.L Protein, bgna Protein, bgn.S Protein, bgn Protein, bgnb Protein
    Sujet

    Background: Biglycan is a 200-350 kD proteoglycan consisting of a 45 kD core protein and two chrondroitin/dermatan sulfate glycosaminoglycan chains. Biglycan binds to TGF-?. It also binds to collagen type I in low ionic strength (less than 3 mM phosphate) buffer. At higher ionic strengths, Biglycan does not bind to collagen type I. It enhances the inhibition effect of TGF-? on osteoclast proliferation at a concentration of 4-20 mg/mL. It also prevents the attachment of CHO cells to fibronectin, with a 50 % inhibition at 17-21 mg/mL.

    Synonym: Biglycan, Bone/Cartilage Proteoglycan I, PG-S1, BGN, SLRR1A

    Poids moléculaire
    40.5 kDa
    UniProt
    P21810
    Pathways
    Glycosaminoglycan Metabolic Process
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