CLEC3B Protein (His tag)

N° du produit ABIN7320183

Détail du produit

Antigène: CLEC3B (C-Type Lectin Domain Family 3, Member B (CLEC3B))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette CLEC3B protéine est marqué à la His tag.

Fonction: Recombinant Mouse CLEC3B/Tetranectin Protein (His Tag)

Séquence: Met 1-Val 202

Attributs du produit: A DNA sequence encoding the mouse CLEC3B (P43025) (Met 1-Val 202) was expressed, with a C-terminal polyhistidinetag.

Pureté: > 95 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CLEC3B (C-Type Lectin Domain Family 3, Member B (CLEC3B))

Autre désignation: CLEC3B/Tetranectin (CLEC3B Produits)

Synonymes: Tna Protein, clec3b Protein, tetn Protein, TN Protein, TNA Protein, C-type lectin domain family 3, member B Protein, C-type lectin domain family 3 member B Protein, tetranectin Protein, C-type lectin domain family 3, member b Protein, Clec3b Protein, clec3b Protein, CLEC3B Protein, tetn Protein

Sujet:

Background: Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes via binding to plasminogen. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to stimulate plasminogen activation and its expression in developing tissues such as developing bone and muscle. Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling. Tetranectin may play a role in the wound healing process. Tetranectin may play a role in neurological diseases and may serve as a diagnostic aid in multiple sclerosis (MS). Tetranectin was found significantly under-expressed in both serum and saliva of metastatic oral squamous cell carcinoma (OSCC) compared to primary OSCC. Tetranectin is thought to enhance proteolytic processes enabling tumor cells to invade and metastasize.

Synonym: Tna

Poids moléculaire: 20.7 kDa

UniProt: P43025