CLEC4E Protein (His tag)

N° du produit ABIN7318316

Détail du produit

Antigène: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette CLEC4E protéine est marqué à la His tag.

Fonction: Recombinant Human CLEC4E/Mincel Protein (His Tag)

Séquence: Arg41-Leu219

Attributs du produit: Recombinant Human C-Type Lectin Domain Family 4 Member E is produced by our Mammalian expression system and the target gene encoding Arg41-Leu219 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Autre désignation: CLEC4E/Mincel (CLEC4E Produits)

Synonymes: CLECSF9 Protein, MINCLE Protein, C86253 Protein, Clecsf9 Protein, Mincle Protein, CLEC4E Protein, C-type lectin domain family 4 member E Protein, C-type lectin domain family 4, member e Protein, C-type lectin domain family 4, member E Protein, CLEC4E Protein, Clec4e Protein, LOC611538 Protein

Sujet:

Background: C-Type Lectin Domain Family 4 Member E (CLEC4E) is a 219 amino acid single-pass type II membrane protein that contains one C-type Lectin domain. It is expressed in monocytes, CLEC4E functions as a downstream target of C/EBP β and is thought to play a role in the inflammatory response, possibly via transcriptional control of C/EBP β. CLEC4E may play a role in the response to inflammatory stimuli in peritoneal macrophages and may be involved in immune surveillance processes under transcriptional control of CEBPB. Human CLEC4E shares 67 % sequence identity with its mouse counterpart, suggesting a similar function between species. CLEC-4E exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to a natural killer gene complex region on human chromosome 12.

Synonym: C-Type Lectin Domain Family 4 Member E, C-Type Lectin Superfamily Member 9, Macrophage-Inducible C-Type Lectin, CLEC4E, CLECSF9, MINCLE

Poids moléculaire: 21.7 kDa

UniProt: Q9ULY5