C1QTNF1 Protein (His tag)

N° du produit ABIN7318213

Détail du produit

Antigène: C1QTNF1 (C1q and Tumor Necrosis Factor Related Protein 1 (C1QTNF1))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette C1QTNF1 protéine est marqué à la His tag.

Fonction: Recombinant Human C1qTNF1/CTRP1 Protein (His Tag)

Séquence: Arg26-Pro281

Attributs du produit: Recombinant Human Complement C1q and Tumor Necrosis Factor-Related Protein 1 is produced by our Mammalian expression system and the target gene encoding Arg26-Pro281 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: C1QTNF1 (C1q and Tumor Necrosis Factor Related Protein 1 (C1QTNF1))

Autre désignation: C1qTNF1/CTRP1 (C1QTNF1 Produits)

Synonymes: C1QTNF1 Protein, CTRP1 Protein, GIP Protein, ZSIG37 Protein, 1600017K21Rik Protein, Zsig37 Protein, Ctrp1 Protein, zgc:113062 Protein, C1q and tumor necrosis factor related protein 1 Protein, C1q and TNF related 1 Protein, C1QTNF1 Protein, c1qtnf1 Protein, C1qtnf1 Protein

Sujet:

Background: C1QTNF1 is a secreted protein,contains 1 C1q domain and 1 collagen-like domain. C1qTNF proteins constitute a highly conserved family of Acrp30/Adiponectin paralogs that share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain and a C-terminal globular domain. C1qTNF proteins are predicted to have trimeric structures that assemble into hexameric and higher order molecular forms. C1QTNF1 is a novel adipokine, providing a significant framework to further address the physiological functions and mechanisms of the action of this family of secreted glycoproteins in normal and disease states. C1QTNF1 increases the production of aldosterone. C1QTNF1 is vastly expressed in obese subjects as well as up-regulated in hypertensive patients, C1QTNF1 is identified molecular link between obesity and hypertension. C1QTNF1 expression may be associated with a low-grade chronic inflammation status in adipose tissues.

Synonym: Complement C1q Tumor Necrosis Factor-Related Protein 1, G Protein-Coupled Receptor-Interacting Protein, GIP, C1QTNF1, CTRP1

Poids moléculaire: 30.2 kDa

UniProt: Q9BXJ1