OB Cadherin Protein (His tag,Fc Tag)

N° du produit ABIN7318215

Détail du produit

Antigène: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette OB Cadherin protéine est marqué à la His tag,Fc Tag.

Fonction: Recombinant Human Cadherin-11/CDH11 Protein (Fc & His Tag)

Séquence: Phe23-Thr617

Attributs du produit: Recombinant Human Cadherin-11 is produced by our Mammalian expression system and the target gene encoding Phe23-Thr617 is expressed with a Fc, 6His tag at the C-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Autre désignation: Cadherin-11/CDH11 (CDH11 Produits)

Synonymes: cad11 Protein, cdhob Protein, osf-4 Protein, Xcad-11 Protein, MGC108014 Protein, OB-cadherin Protein, cadherin-11 Protein, Cad11 Protein, cdhvn Protein, vnc Protein, CAD11 Protein, CDHOB Protein, OB Protein, OSF-4 Protein, cadherin 11 Protein, cadherin 11, type 2, OB-cadherin (osteoblast) Protein, cadherin 11 S homeolog Protein, CDH11 Protein, cdh11 Protein, Cdh11 Protein, cdh11.S Protein

Sujet:

Background: Cadherin-11, also known as OSF-4, Osteoblast cadherin and CDH11, is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, may thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. It is shown that cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.

Synonym: Cadherin 11 Type 2 OB-cadherin (Osteoblast), Cadherin 11 Type 2 OB-Cadherin (Osteoblast) Isoform CRA_c, CDH11

Poids moléculaire: 93.5 kDa

UniProt: Q96CZ9