CD36 Protein (CD36) (Fc Tag)

N° du produit ABIN7320791

Protéine Recombinant CD36 exprimée dans Human Cells.

Aperçu rapide pour CD36 Protein (CD36) (Fc Tag) (ABIN7320791)

Antigène: CD36

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Souris

Source: Human Cells

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette CD36 protéine est marqué à la Fc Tag.

Fonction: Recombinant Mouse CD36/SCARB3 Protein (Fc Tag)(Active)

Séquence: Gly30-Lys439

Attributs du produit: Recombinant Mouse Platelet Glycoprotein 4 is produced by our Mammalian expression system and the target gene encoding Gly30-Lys439 is expressed with a Fc tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Mouse CD36-Fc at 10μg/ml(100 μl/well) can bind Human RSPO1-His(Cat: PKSH033007). The ED50 of Mouse CD36-Fc is 0.07 ug/mL

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CD36

Autre désignation: CD36/SCARB3

Sujet:

Background: Dermatopontin is a widely expressed noncollagenous protein component of the extracellular matrix. It is a 22 kDa molecule that is tyrosine sulfated but not glycosylated. Dermatopontin is down regulated in fibrotic growths such as leiomyoma and scar tissue, inhibits cell proliferation, accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation, Dermatopontin deficient mice exhibit altered collagen matrix deposition and organization. Dermatopontin seems to mediate adhesion by cell surface integrin binding, may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment, and enhances TGFB1 activity (By similarity). Dermatopontin promotes bone mineralization under the control of the vitamin D receptor and inhibits BMP-2 effects on osteoblast precursors.

Synonym: Glycoprotein IIIb, GPIIIB, PAS IV, PAS-4, Platelet glycoprotein IV, GPIV, CD36

Poids moléculaire: 73.5 kDa

UniProt: Q08857

Pathways: Signalisation TLR, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins