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CLIC2 Protein (His tag)

CLIC2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318307
  • Antigène Voir toutes CLIC2 Protéines
    CLIC2 (Chloride Intracellular Channel 2 (CLIC2))
    Type de proteíne
    Recombinant
    Origine
    Humain
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CLIC2 protéine est marqué à la His tag.
    Fonction
    Recombinant Human CLIC2 Protein (His Tag)
    Séquence
    Met 1-Ser247
    Attributs du produit
    Recombinant Human Chloride Intracellular Channel Protein 2 is produced by our E.coli expression system and the target gene encoding Met1-Ser247 is expressed with a 6His tag at the N-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CLIC2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 20 % Glycerol, pH 8.0.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    CLIC2 (Chloride Intracellular Channel 2 (CLIC2))
    Autre désignation
    CLIC2 (CLIC2 Produits)
    Synonymes
    zgc:92762 Protein, CLIC2 Protein, CLIC2b Protein, MRXS32 Protein, XAP121 Protein, chloride intracellular channel 2 Protein, clic2 Protein, CLIC2 Protein, Clic2 Protein
    Sujet

    Background: Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells, it regulatescellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, channel activity depends on the pH . CLIC2 is involved in regulating membrane potential and organic solute transport. CLIC2 modulates the activity of RYR2 and inhibits Calcium influx. CLIC2 can be detected in the adult brain, liver, lung, heart, stomach, spleen and testis. It is expressed in fetal liver and adult skeletal muscle. CLIC2 is a potential candidate for one of many diseases linked to Xq28.

    Synonym: Chloride Intracellular Channel Protein 2, XAP121, CLIC2

    Poids moléculaire
    30.5 kDa
    UniProt
    O15247
    Pathways
    Negative Regulation of Transporter Activity
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